Sounds like it might be worth picking up some decent kick drum samples then. For me usually I will try and start with a good kick drum sample, then I'll probably add some compression, maybe getting 5-6dB of compression with 10ms or so attack to let some 'bite' through. This both fills the sound up, gives you a nice solid sound and can give you some bite to the attack.
EQ...quite often you don't need that much midrange in the kick, a nice high end attack, a nice solid low end but having too much mid can crowd things, so I might scoop some mid range out, esp if it's quite a resonant kick. Then maybe add some highs EQ for a nice crisp bite. Parallel compression can work really well too, instead of using the compressor as an insert, use it on a aux send and balance the normal and compressed signals. A little tube style distortion can really bring out the detail and punch of a kick, not a lot, keep it subtle, try using a tube emulator on an aux send.
Sometimes the kick is just bad or wrong for the track. Sometimes layering works, take the low end from one kick with the bite of another, low pass filter the low end, hi pass filter the high end. Combine the two.
Sometimes it's not the kick at all that is the issue, other frequencies are getting in the way of it, so 9/10 I'll put a hi pass filter on everything else other than the kick and the bass and really clean up the bottom end of the mix, maybe cutting everything below 150hz.
Side-chaining can be very effective (ie: the compressor/side chain plugin ducks the bassline when the kick strikes), but if you are using an offbeat bassline not hugely necessary, esp if you tweek the release of the bass sound so it's not overlapping the kick too much. If you are using a 16th part synth bass, side-chaining can really get things pumping and grooving.
Try moving the bassline up an octave, sometimes that can really clean up the low end of the mix. You only have so much space in a mix and you have a choice between the kick and the bass as to what provides the low energy, in some music the bass is king and the kicks are actually quite thin, in most club music the kick is king and the bass is actually quite a thin sound with a lot of the bottom end taken off. Sometimes the 'bass' line is actually less of a low end thing and more something that sits in the midrange.
The big question worth asking is, what do you actually want it to sound like? Can you name some tracks with kick drums you particularly like on?